Bruce N. Ames 2002 Publications

450. Gogvadze, V., Walter, B., and Ames, B.N. (2002) Fe2+ Induces a Transient Ca2+ Release from Rat Liver Mitochondria. Arch. Biochem. Biophys. 398, 198-202. check for PDF

451. Walter, P.B., Knutson, M.D., Paler-Martinez, A., Lee, S., Xu, Y., Viteri, F.E., and Ames, B.N. (2002) Iron Deficiency and Iron Excess Damage Mitochondria and Mitochondrial DNA in Rats. Proc. Natl. Acad. Sci. U.S.A. 99, 2264-2269. check for PDF

452. Atamna, H., Walter, P.B., and Ames, B. N. (2002). The Role of Heme and Iron-Sulfur Clusters in Mitochondrial Biogenesis, Maintenance, and Decay with Age. Arch. Biochem. Biophys. 397, 345-353. check for PDF

453. Ames, B. N., Elson-Schwab, I., and Silver, E. (2002) High-Dose Vitamins Stimulate Variant Enzymes with Decreased Coenzyme-Binding Affinity (Increased Km): Relevance to Genetic Disease and Polymorphisms. Am J. Clin. Nutr. 75, 616-658. check for PDF

454. Liu, J., Head, E., Gharib, A.M., Yuan, W., Ingersoll, R.T. Hagen, T.M., Cotman, C.W., and Ames, B.N. (2002) Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and/or R-α-Lipoic Acid. Proc. Natl. Acad. Sci. U.S.A. 99, 2356-2361. check for PDF

455. Hagen, T.M., Liu, J., Lykkesfeldt, J., Wehr, C.M., Ingersoll, R.T., Vinarsky, V., Bartholomew, J.C., and Ames, B.N. (2002) Feeding Acetyl-L-Carnitine and Lipoic Acid to Old Rats Significantly Improves Metabolic Function while Decreasing Oxidative Stress. Proc. Natl. Acad. Sci. U.S.A. 99, 1870-1875. check for PDF

456. Liu, J., Killilea, D.W., and Ames, B.N. (2002) Age-associated Mitochondrial Oxidative Decay: Improvement of Carnitine Acetyltransferase Substrate Binding Affinity and Activity in Brain by Feeding Old Rats Acetyl-L-Carnitine and/or R-α-Lipoic Acid. Proc. Natl. Acad. Sci. U.S.A. 99, 1876-1881. check for PDF

457. Liu, L. Atamna, H., Kuratsune, H., and Ames, B.N. (2002) Delaying Brain Mitochondrial Decay and Aging with Mitochondrial Antioxidants and Metabolites. Ann. N.Y. Acad. Sci. 959, 133-166. check for PDF

458. de Grey, A.B.D., Ames, B.N., Andersen, J.K., Bartke, A., Campisi, J., Heward, C.B., McCarter, R.J.M., and Stock, G. (2002) Time to Talk SENS: Critiquing the Immutability of Human Aging. Ann. N.Y. Acad. Sci. 959, 452-462. check for PDF

459. Jiang, Q., Christen, S., Shigenaga, M.K., and Ames, B.N. (2002) γ-Tocopherol: The Neglected Form of Vitamin E: New Functions, New Interest. In: Oxidative Stress and Aging: Advances in Basic Science, Diagnostics and Intervention, R. G. Cutler and H. Rodriguez, eds. (World Scientific Publishing Co., River Edge, NJ), pp. 567-579. check for PDF

460. Gold, L.S., Slone, T.H., Manley, N.B., and Ames, B.N. (2002) Misconceptions about Pollution, Pesticides, and the Prevention of Cancer. In: Human and Ecological Risk Assessment: Theory and Practice, D. J. Paustenbach, ed. (John Wiley & Sons, New York), pp. 1415-1460. check for PDF

460a. Halsted, C.H., Villanueva, J.A., Devlin, A.M., Niemelä, O., Parkkila, S., Garrow, T.A., Wallock, L.M., Shigenaga, M.K., Melnyk, S., and James, S.J. (2002) Folate Deficiency Disturbs Hepatic Methionine Metabolism and Promotes Liver Injury in the Ethanol-Fed Micropig. Proc. Natl. Acad. Sci. U.S.A. 99, 10072-10077.

461. Ames, B.N. (2002) The Causes and Prevention of Cancer: Do Federal Regulations Help? Washington Roundtable on Science & Public Policy (George C. Marshall Institute, Washington, D.C.). check for PDF

462. Bharath, S., Cochran, B.C., Hsu, M., Liu, J., Ames, B.N., and Andersen, J.K. (2002) Pre-treatment with Lipoic Acid Alleviates the Effects of GSH Depletion in PC12 Cells: Implications for Parkinson's Disease Therapy. Neurotoxicology 23, 479-486. check for PDF

463. Ames, B. N. and Wakimoto, P. (2002) Are Vitamin and Mineral Deficiencies a Major Cancer Risk? Nat. Rev. Cancer 2, 694-704. check for PDF

464. Head, E., Liu, J., Hagen, T.M., Muggenburg, B.A., Milgram, N.W., Ames, B.N., and Cotman, C.W. (2002) Oxidative Damage Increases with Age in a Canine Model of Human Brain Aging. J. Neurochem. 82, 375-381. check for PDF

465. Jiang, Q., Lykkesfeldt, J., Shigenaga, M.K., Shigeno, E.T., Christen, S., and Ames, B.N. (2002) γ-Tocopherol Supplementation Inhibits Protein Nitration and Ascorbate Oxidation in Rats with Inflammation. Free Radic. Biol. Med. 33, 1534-1542. check for PDF

466. Christen, S., Jiang, Q., Shigenaga, M.K., and Ames, B.N. (2002) Analysis of Plasma Tocopherols α-, γ-, and 5-Nitro-γ-Tocopherol, in Rats with Inflammation by HPLC Coulometric Detection. J. Lipid Res. 43, 1978-1985. check for PDF

467. Atamna, H., Killilea, D.W., Killilea, A.N., and Ames, B.N. (2002) Heme Deficiency May Be a Factor in the Mitochondrial and Neuronal Decay of Aging. Proc. Natl. Acad. Sci. U.S.A. 99, 14807-14812. check for PDF

468. Ho, E., and Ames, B.N. (2002) Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFKB and AP1 DNA Binding, and Affects DNA Repair in a Rat Glioma Cell Line. Proc Natl Acad Sci U S A 99, 16770-16775. check for PDF 469. Gold, L.S., Slone, T.H., Manley, N.B., and Ames, B.N. (2002) Misconceptions About the Causes of Cancer, The Fraser Institute, Vancouver, BC, Canada. check for PDF

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Contact Information

Mailing Address:

Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Administrative Assistant,
Teresa Klask
Phone: (510) 450-7627
CHORI E-mail: tklask@chori.org

The CHORI-bar

You might ask yourself...

  • Can a nutrition bar, improve metabolism naturally, without drugs, secondarily improve quality of lifeof individuals with the co-morbidities of obesity, such as asthma, diabetes, and hypertension?

Well ... The Ames lab is currently creating just that type of nutrition bar

Select this link for a copy of our CHORI-Bar History document


Downloadable Media

The downloadable media section is constantly being updated.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.

Dr. Ames current lecture abstract presented to Moffitt Cancer Center on May 2015. Lecture Title: Vitamin and Mineral Inadequacy Accelerates Aging-Associated Diseases
Select this Link for a copy of the abstract